Jackson Laboratory "Genetic Background: understanding its importance in mouse-based biomedical research"

Last Review Date: January 4, 2018

This mouse genetics resource manual outlines The Jackson Laboratory's Genetic Quality Control Program for preventing genetic contamination and its Genetic Stability Program for slowing genetic drift. Additionally, it discusses the importance of understanding substrains and genetic background in genetic research and encourages researchers to use proper nomenclature in all their research communications.

To receive a PDF copy of the manual, see the following web link:

https://www.semanticscholar.org/paper/Genetic-Background-%3A-Understanding-its-importance-Jackson

In addition, a copy of The Jackson Laboratory Handbook on Genetically Standardized Mice, has been provided to the Center for Environmental Health Sciences, the Center for Functional and Structural Neurosciences, and Laboratory Animal Resources to use as reference material.