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Biophysics and Structural Biology

Faculty Program Interests

 

Bruce Bowler

Bruce Bowler

Professor

bruce.bowler@umontana.edu

Biochemistry & Biophysics

Chemistry

Protein folding, conformationally-gated electron transfer and structural biology of cytochromes.

 

Klara Briknarova

Klára Briknarová

Associate Professor

klara.briknarova@umontana.edu

Biochemistry & Biophysics

Chemistry

Nuclear magnetic resonance (NMR) spectroscopy, biochemical and biophysical techniques to study the structure, function and dynamics of biological macromolecules.

 

Bradley Layton

Bradley Layton

Associate Professor

bradley.layton@umontana.edu

Biochemistry & Biophysics

Nanoscale biomechanics; drought resistance mechanisms; anthropogenic entropy acceleration.

 

Michele McGuirl

Michele McGuirl

Professor

michele.mcguirl@umontana.edu

Cellular, Molecular & Microbial Biology

Biochemistry & Biophysics

Prion protein aggregation and electron transfer through tyrosyl radicals.

 

Sandy Ross

J.B. Alexander (Sandy) Ross

Professor

sandy.ross@umontana.edu

Biochemistry & Biophysics

Chemistry

Use of ensemble-average and single-molecule fluorescence to investigate the relationship between biological function and structural dynamics in protein-protein and protein-membrane interactions.

 

Steve Sprang

Stephen R. Sprang

Professor

stephen.sprang@umontana.edu

Cellular, Molecular & Microbial Biology

Biochemistry & Biophysics

Structural and biophysical mechanisms in signal transduction.

Recent publications related to Biophysics and Structural Biology from UM Faculty:

A cytochrome C electron transfer switch modulated by heme ligation and isomerization of a peptidyl-prolyl bond. Bandi S, Bowler BE. Biopolymers. 2013 Apr;100(1):114-24. doi: 10.1002/bip.22164. PMID: 23335173

Dissociation of recombinant prion protein fibrils into short protofilaments: implications for the endocytic pathway and involvement of the N-terminal domain. Qi X, Moore RA, McGuirl MA. Biochemistry. 2012 Jun 5;51(22):4600-8. Epub 2012 May 23. PMID: 22591453

Molecular chaperoning function of Ric-8 is to fold nascent heterotrimeric G protein α subunits. Chan P, Thomas CJ, Sprang SR, Tall GG. Proc Natl Acad Sci U S A. 2013 Mar 5;110(10):3794-9. doi: 10.1073/pnas.1220943110. Epub 2013 Feb 19. PMID: 23431197

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